Xercise

Why Intensity Trumps Duration

By PJ Glassey / / Comments Off on Why Intensity Trumps Duration

The Endothelial Edge: Why Intensity Trumps Duration for Cardiovascular Longevity As an anti-aging researcher, exercise physiologist, author, and inventor of the X Gym exercise methodology, I have spent decades perfecting a 21-minute protocol designed to maximize physiological adaptation. The mainstream often pushes “more is better” regarding exercise volume, but the molecular data suggest a different…

Alzheimer’s Forgotten (or suppressed) Causes and Cures

By PJ Glassey / / Comments Off on Alzheimer’s Forgotten (or suppressed) Causes and Cures

Reversing Alzheimer’s: Causes and Forgotten Cures  This summary, from a 2025 article by “A Midwestern Doctor,” critiques the conventional approach to Alzheimer’s disease (AD) and outlines alternative, forgotten therapies that address root causes. This summary is a deep dive for science nerds who want to drink out of the fire hose from current health professionals…

The Underestimated Power of Vigorous Exercise

By PJ Glassey / / Comments Off on The Underestimated Power of Vigorous Exercise

Science Got it Wrong: New Data on Intensity Rewrites Longevity Guidelines For decades, public health guidelines have operated under a metabolic assumption: 1 minute of vigorous-intensity activity (VIA) is equivalent to 2 minutes of moderate-intensity activity (MIA). This 1:2 ratio, based on estimated energy expenditure or METs (Metabolic Equivalents), focused on calorie burn rather than…

Another Reason CICO Is Sh*t Science: The Calorie Cost of Poop They Never Address

By PJ Glassey / / Comments Off on Another Reason CICO Is Sh*t Science: The Calorie Cost of Poop They Never Address

Fecal Energy Loss and CICO Theory The CICO model, which is fundamentally based on the First Law of Thermodynamics (energy conservation), states that weight change is determined by the difference between energy intake and energy expenditure. ΔBody Weight∝(Energy Intake)−(Energy Expenditure) However, the “Calories In” part of this equation is complicated by the fact that the…

X Gym’s 21-Minute Methodology Boosts GLP-1 (and more)

By PJ Glassey / / Comments Off on X Gym’s 21-Minute Methodology Boosts GLP-1 (and more)

Microbiome Rewritten: X Gym’s 21-Minute Methodology Boosts GLP-1/PYY & Butyrate (No Peptide Injection Required) Our 21-minute, twice-weekly, high-intensity functional training protocol is optimally structured to generate powerful, acute hormonal signals that reinforce appetite-suppressing and metabolic benefits, setting the gut microbiome up to support weight-loss goals. Here are the ways it accomplishes this:  1. Augmenting Anorexigenic…

The Secret Life of Sleep: Your Nightly Prescription for Health, Anti-Aging, and Longevity

By PJ Glassey / / Comments Off on The Secret Life of Sleep: Your Nightly Prescription for Health, Anti-Aging, and Longevity

We all know sleep is important. It’s when our body “detoxes and repairs,” right? But what if I told you that optimizing your sleep phases is one of the most powerful, non-negotiable anti-aging strategies you possess? Understanding this unlocks a new level of healthspan extension. Let’s pull back the curtain on what’s really happening when…