The Mechanical Shield: How Vigorous Exercise Triggers Apoptosis in Circulating Tumor Cells As a functional medicine researcher and inventor of X Gym’s high-intensity training system, I have spent decades analyzing how we can optimize the human machine to resist the diseases of aging. While many focus on the metabolic or hormonal benefits of exercise, there…
Read MoreScience Got it Wrong: New Data on Intensity Rewrites Longevity Guidelines For decades, public health guidelines have operated under a metabolic assumption: 1 minute of vigorous-intensity activity (VIA) is equivalent to 2 minutes of moderate-intensity activity (MIA). This 1:2 ratio, based on estimated energy expenditure or METs (Metabolic Equivalents), focused on calorie burn rather than…
Read MoreSome biohackers and longevity seekers are using the diabetes drug Metformin off-label as a “hack” for better health and longevity, but the research indicates that might not be such a good idea. Studies suggest that metformin may blunt key physiological benefits derived from exercise, raising caution for its use in healthy, physically active individuals. Metformin,…
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